妊娠合并结构性心脏病患者妊娠结局的影响因素

苏炳峰1 苏丽香2 许巧能3

1. 厦门大学附属第一医院妇产科 2. 安溪县医院妇产科3. 福建中医药大学附属人民医院药剂科

摘要：目的：探究妊娠合并结构性心脏病患者妊娠结局的影响因素。方法：选取182例妊娠合并结构性心脏病患者，采用单因素与多因素分析妊娠合并结构性心脏病患者妊娠结局的影响因素。结果：单因素分析显示妊娠合并结构性心脏病患者发生不良妊娠结局与孕次、体质量指数无关（P＞0.05）;多因素分析显示妊娠年龄、心功能分级、心脏手术治疗、肺动脉压力、血红蛋白含量、心律失常是妊娠合并结构性心脏病患者发生不良妊娠结局的危险因素（P＜0.05）。结论：对合并高危因素患者实施孕期及围产期全面综合指导，可一定程度上减少不良妊娠结局的发生。

关键词：妊娠;结构性心脏病;妊娠结局;

Factors influencing pregnancy outcomes in pregnant patients with structural heart disease

SU Bingfeng1,SU Lixiang2,XU Qiaoneng3.(1. Dept. of Obstetrics & Gynecology,the 1stAffiliated Hospital of Xiamen University,Xiamen 361000;2. Dept. of Obstetrics & Gynecology,Anxi County Hospital,Anxi 362400;3. Dept. of Pharmacy,the People′s Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350000,China)

Abstract Objective: To explore the influencing factors of pregnancy outcome in pregnant patients with structural heart disease. Methods: 182 pregnant patients with structural heart disease were selected, and single and multiple factors were used to analyze the influencing factors of pregnancy outcome in pregnant patients with structural heart disease. Results: Univariate analysis showed that adverse pregnancy outcomes in pregnant patients with heart disease were not related to gravidity and boby mass index(P>0.05); while multifactorial analysis revealed that pregnant age, cardiac functional grading, cardiac surgery, pulmonary artery pressure, hemoglobin, and arrhythmia were risk factors for the incidence of adverse pregnancy outcomes in pregnant women with structural heart disease (P< 0. 05). Conclusion: Comprehensive and overall guidance during pregnancy and perinatal period should be given to patients with the above high-risk factors to minimize the occurrence of adverse pregnancy outcomes.

Keywords:pregnancy;structural heart disease; pregnancy outcomes

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