PAN Wenwen, WANG Nan

( Department of Nursing, Zhengzhou 460 Hospital, Zhengzhou 450000, 

China)

Abstract Objective To observe the effects of salvianolic tablet assisted repetitive transcranial magnetic stimulation ( rTMS) on the recovery of neurological function in patients with ischemic stroke. Methods 110 patients with ischemic stroke were selected as the study subjects and randomly divided into two groups, with 55 cases in each group. The patients in routine group were received routine treatment combined with rTMS treatment. The patients in combination group were treated with combination of paeonol tablets and rTMS. The inflammation indicators, immune function, brain nerve function, cognitive and motor function between the two groups were compared. Results After treatment, the levels of IL-6, IL-1β and CRP in the combination group were lower than those in the routine group, showing a statistically significant difference ( P<0.05) . The expression levels of CD4+/CD3+ and CD4+/CD8+ in the combination group were higher than those in the routine group, while the expression levels of CD8+/CD3+ were lower than those in the routine group ( P<0.05) . The MMSE, MoCA scores, FMA, and MBI scores in the combined group after 1 and 4 weeks of treatment were higher than those in the routine group ( P < 0. 05) . Conclusion Paeonol tablets assisted with rTMS improves effectively the inflammatory response, immune function, and neurological function of patients with ischemic stroke.

Keywords: ischemic stroke; paeonol tablets; repetitive transcranial magnetic stimulation; neurological function; rehabilitation situation

DOI:10.19296/j.cnki.1008-2409.2024-03-033

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